Stem cells are undifferentiated cells capable of self-renewal, differentiation, and tissue repair due to their unique regenerative properties. They hold the potential to transform male infertility treatment, particularly by enhancing sperm quality and restoring erectile function.
Several preclinical studies have explored the use of stem cell-based therapies for erectile dysfunction (ED), especially in cases caused by cavernous nerve injury, Peyronie’s disease, diabetes, aging, and hyperlipidemia. These studies have consistently demonstrated promising results in restoring erectile function and improving vascular health in animal models.
Stem cell therapy involves the use of regenerative cells to repair or replace damaged tissues. In the context of ED, stem cells can help regenerate nerve tissues and blood vessels in the penis that are critical for achieving an erection.
Preclinical animal studies have revealed that erectile dysfunction is often linked to cavernous nerve injury or diabetic complications. Stem cells promote healing by releasing growth factors into the bloodstream and/or by migrating to major pelvic ganglia. This process involves cellular contact, paracrine signaling, and differentiation to regenerate erectile tissue.
However, it is important to note that stem cell therapy is still considered an investigational approach for ED. It is not yet approved by the US FDA and is not routinely recommended by medical bodies such as the American Urological Association (AUA), the European Association of Urology (EAU), or the Sexual Medicine Society of North America (SMSNA).
Early clinical trials show encouraging results—stem cell therapy has restored sufficient erectile function in previously impotent men, allowing them to achieve spontaneous intercourse. This is a groundbreaking step toward offering long-term solutions for ED, especially for those who do not respond to conventional medications or treatments.
Curious about advanced options for erectile dysfunction? Book your appointment with Androplus to explore cutting-edge regenerative therapies under expert supervision.
